Polynucleotides & PDRN Therapy with Microneedling: Dublin’s Hottest Skin Rejuvenation Treatment
- MADA Clinic and Spa
- Aug 13
- 2 min read
In the world of advanced skin rejuvenation, few treatments are making waves quite like polynucleotides and PDRN therapy—especially when paired with microneedling. Here in Dublin, clients are seeking out this innovative combination for its ability to restore skin health, improve texture, and deliver a radiant, youthful glow with minimal downtime.

What Are Polynucleotides & PDRN?
Polynucleotides are naturally derived DNA fragments that work at a cellular level to:
Stimulate collagen production
Boost cell regeneration
Improve skin hydration
Enhance tissue repair
PDRN (Polydeoxyribonucleotide) is a specific type of polynucleotide sourced from purified salmon DNA, known for its exceptional anti-inflammatory and healing properties. Together, these bio-stimulators help repair damaged skin, reduce fine lines, and promote a smoother, healthier complexion.

Why Combine Them with Microneedling?
Microneedling creates controlled micro-injuries in the skin using fine needles, which:
Trigger the body’s natural healing response
Increase collagen and elastin production
Enhance serum penetration for deeper results
When we infuse polynucleotides and PDRN during microneedling, the benefits multiply:
Deeper absorption of rejuvenating DNA molecules
Accelerated healing and reduced redness post-treatment
Maximized collagen stimulation for firmer skin
Benefits You Can Expect
Improved skin tone and texture
Reduction in fine lines and wrinkles
Brighter, more radiant complexion
Stronger skin barrier and hydration levels
Visible results after just a few sessions
Who Is It For?
This treatment is ideal for those looking to:
Address early signs of aging
Improve acne scars and pigmentation
Restore vitality to tired or dull skin
Speed up recovery after other aesthetic procedures
Polynucleotides & PDRN Microneedling in Dublin
At our Dublin skin clinic, we use medical-grade microneedling devices and premium PDRN serums to ensure maximum results with minimal discomfort. Each treatment is tailored to your skin’s needs, making it safe for all skin types and tones.
Ready to experience Dublin’s most talked-about skin therapy?

Book your Polynucleotide & PDRN Microneedling session today and give your skin the boost it deserves.